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TRPC3 (NM_003305) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Overview

Recombinant protein of human transient receptor potential cation channel, subfamily C, member 3 (TRPC3), transcript variant 2

Synonyms

SCA41; TRP3

Gene ID

7222

UniProt

Q13507

Accession Number mRNA

NM_003305

Chromosomal Location

4q27

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane

Molecular Weight

97.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

TRPC3

Species

Human

Protein ID

NP_003296

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/7222

Uniprot URL

https://www.uniprot.org/uniprot/Q13507

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_003305

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_003296

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