GNG13 (NM_016541) Human Recombinant Protein

Product Specifications

Background

Heterotrimeric G proteins, which consist of alpha (see MIM 139320), beta (see MIM 139380), and gamma subunits, function as signal transducers for the 7-transmembrane-helix G protein-coupled receptors. GNG13 is a gamma subunit that is expressed in taste, retinal, and neuronal tissues and plays a key role in taste transduction (Li et al., 2006 [PubMed 16473877]) .[supplied by OMIM, Oct 2009]

Overview

Recombinant protein of human guanine nucleotide binding protein (G protein), gamma 13 (GNG13)

Synonyms

G (gamma) 13; h2-35

Gene ID

51764

UniProt

Q9P2W3

Accession Number mRNA

NM_016541

Chromosomal Location

16p13.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Chemokine signaling pathway, Taste transduction

Field of Research

Chemokine signaling pathway, Taste transduction

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

7.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.