TNFSF18 (NM_005092) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [provided by RefSeq, Jul 2008]
Synonyms
AITRL; GITRL; hGITRL; TL6; TNLG2A
Gene ID
8995
UniProt
Q9UNG2, A0A0U5JXL4
Accession Number mRNA
NM_005092
Chromosomal Location
1q25.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Cytokine-cytokine receptor interaction
Field of Research
Cytokine-cytokine receptor interaction
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
22.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TNFSF18
Species
Human
Protein ID
NP_005083
Overview
Recombinant protein of human tumor necrosis factor (ligand) superfamily, member 18 (TNFSF18)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8995
Uniprot URL
https://www.uniprot.org/uniprot/Q9UNG2
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005092
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005083
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