CACNG5 (NM_145811) Human Recombinant Protein
Selected Variant
PH37027M5
Size: 20 µg
Product Specifications
Background
The protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP) . TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type I TARP and a calcium channel gamma subunit. This gene is a susceptibility locus for schizophrenia and bipolar disorder. [provided by RefSeq, Dec 2010]
Overview
Recombinant protein of human calcium channel, voltage-dependent, gamma subunit 5 (CACNG5), transcript variant 1
Synonyms
MGC126656; MGC126682
Gene ID
27091
UniProt
Q9UF02
Accession Number mRNA
NM_145811
Chromosomal Location
17q24.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway
Field of Research
Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
30.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CACNG5
Species
Human
Protein ID
NP_665810
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/27091
Uniprot URL
https://www.uniprot.org/uniprot/Q9UF02
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_145811
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_665810
Price
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