Nkx6.2 (NKX6-2) (NM_177400) Human Recombinant Protein
Product Specifications
Background
Transcription factor with repressor activity involved in the regulation of axon-glial interactions at myelin paranodes in oligodendrocytes. Binds to the consensus DNA sequence 5'- (A/T) TTAATGA-3'. In oligodendrocytes, binds to MBP and PLP1 promoter regions.[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human NK6 homeobox 2 (NKX6-2)
Synonyms
GTX; NKX6.2; NKX6B; SPAX8
Gene ID
84504
UniProt
Q9C056
Accession Number mRNA
NM_177400
Chromosomal Location
10q26.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transcription Factors
Molecular Weight
29.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NKX6-2
Species
Human
Protein ID
NP_796374
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/84504
Uniprot URL
https://www.uniprot.org/uniprot/Q9C056
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_177400
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_796374
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