H2BC18 (NM_001024599) Human Recombinant Protein
Product Specifications
Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family and is found in a histone cluster on chromosome 1. [provided by RefSeq, Aug 2015]
Synonyms
FLJ35099; FLJ56780; FLJ56787; MGC131639
Gene ID
440689
UniProt
Q5QNW6
Accession Number mRNA
NM_001024599
Chromosomal Location
1q21.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Systemic lupus erythematosus
Field of Research
Systemic lupus erythematosus
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
13.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HIST2H2BF
Species
Human
Protein ID
NP_001019770
Overview
Recombinant protein of human histone cluster 2, H2bf (HIST2H2BF)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/440689
Uniprot URL
https://www.uniprot.org/uniprot/Q5QNW6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001024599
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001019770
Curated Selection
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