KLHDC5 (KLHL42) (NM_020782) Human Recombinant Protein
Product Specifications
Background
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR (KLHL42) E3 ubiquitin ligase complex mediates the ubiquitination and subsequent degradation of KATNA1. Involved in microtubule dynamics throughout mitosis.[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human kelch domain containing 5 (KLHDC5)
Synonyms
Ctb9; KLHDC5
Gene ID
57542
UniProt
Q9P2K6, B2RNT7
Accession Number mRNA
NM_020782
Chromosomal Location
12p11.22
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
56.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
KLHL42
Species
Human
Protein ID
NP_065833
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/57542
Uniprot URL
https://www.uniprot.org/uniprot/Q9P2K6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_020782
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_065833
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