NECAP1 (NM_015509) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein containing two characteristic WXXF motifs. The encoded protein localizes to clathrin-coated vesicles, where it binds components of the adapter protein complexes and aids in endocytosis. Loss of function of this gene results in early infantile epileptic encephalopathy-21. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Synonyms
DEE21; EIEE21
Gene ID
25977
UniProt
Q8NC96
Accession Number mRNA
NM_015509
Chromosomal Location
12p13.31
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
29.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NECAP1
Species
Human
Protein ID
NP_056324
Overview
Recombinant protein of human NECAP endocytosis associated 1 (NECAP1), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/25977
Uniprot URL
https://www.uniprot.org/uniprot/Q8NC96
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_015509
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_056324
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