Apolipoprotein L 1 (APOL1) (NM_003661) Human Recombinant Protein
Product Specifications
Background
This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
Synonyms
APO-L; APOL; APOL-I; FSGS4
Gene ID
8542
UniProt
O14791, Q2KHQ6
Accession Number mRNA
NM_003661
Chromosomal Location
22q12.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Secreted Protein, Transmembrane
Molecular Weight
41.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
APOL1
Species
Human
Protein ID
NP_003652
Overview
Recombinant protein of human apolipoprotein L, 1 (APOL1), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8542
Uniprot URL
https://www.uniprot.org/uniprot/O14791
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003661
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003652
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