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Apolipoprotein L 1 (APOL1) (NM_003661) Human Recombinant Protein

Product Specifications

Background

This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]

Overview

Recombinant protein of human apolipoprotein L, 1 (APOL1), transcript variant 1

Synonyms

APO-L; APOL; APOL-I; FSGS4

Gene ID

8542

UniProt

O14791, Q2KHQ6

Accession Number mRNA

NM_003661

Chromosomal Location

22q12.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Secreted Protein, Transmembrane

Molecular Weight

41.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

APOL1

Species

Human

Protein ID

NP_003652

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/8542

Uniprot URL

https://www.uniprot.org/uniprot/O14791

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_003661

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_003652

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