Interferon alpha 8 (IFNA8) (NM_002170) Human Recombinant Protein
Product Specifications
Background
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human interferon, alpha 8 (IFNA8)
Synonyms
IFN-alphaB
Gene ID
3445
UniProt
P32881
Accession Number mRNA
NM_002170
Chromosomal Location
9p21.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Antigen processing and presentation, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Regulation of autophagy, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway
Field of Research
Antigen processing and presentation, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Regulation of autophagy, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Secreted Protein
Molecular Weight
21.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
IFNA8
Species
Human
Protein ID
NP_002161
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3445
Uniprot URL
https://www.uniprot.org/uniprot/P32881
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002170
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002161
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