CYP2R1 (NM_024514) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency. [provided by RefSeq, Jul 2008]
Synonyms
MGC4663
Gene ID
120227
UniProt
Q6VVX0
Accession Number mRNA
NM_024514
Chromosomal Location
11p15.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, P450, Transmembrane
Molecular Weight
57.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CYP2R1
Species
Human
Protein ID
NP_078790
Overview
Recombinant protein of human cytochrome P450, family 2, subfamily R, polypeptide 1 (CYP2R1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/120227
Uniprot URL
https://www.uniprot.org/uniprot/Q6VVX0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_024514
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_078790
Curated Selection
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