Tyrosine Hydroxylase (TH) (NM_000360) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]
Synonyms
DYT5b; DYT14; TYH
Gene ID
7054
UniProt
P07101
Accession Number mRNA
NM_000360
Chromosomal Location
11p15.5
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Metabolic pathways, Parkinson's disease, Tyrosine metabolism
Field of Research
Metabolic pathways, Parkinson's disease, Tyrosine metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
55.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TH
Species
Human
Protein ID
NP_000351
Overview
Recombinant protein of human tyrosine hydroxylase (TH), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7054
Uniprot URL
https://www.uniprot.org/uniprot/P07101
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_000360
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_000351
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS9713742-01 48 Tests
Human Vesicle-Associated Membrane Protein 2 (VAMP2) ELISA Kit
Ask
View Details 
MBS9713742-02 96 Tests
Human Vesicle-Associated Membrane Protein 2 (VAMP2) ELISA Kit
Ask
View Details MBS9713742-03 5x 96 Tests
Human Vesicle-Associated Membrane Protein 2 (VAMP2) ELISA Kit
Ask
View Details