EN2 (NM_001427) Human Recombinant Protein
Product Specifications
Background
Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. [provided by RefSeq, Jul 2008]
Synonyms
AUTS1, AUTS10; engrailed-2; engrailed homeobox 2; engrailed homolog 2
Gene ID
2020
UniProt
P19622
Accession Number mRNA
NM_001427
Chromosomal Location
7q36.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, ES Cell Differentiation/IPS
Molecular Weight
34 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
EN2
Species
Human
Protein ID
NP_001418
Overview
Recombinant protein of human engrailed homeobox 2 (EN2)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2020
Uniprot URL
https://www.uniprot.org/uniprot/P19622
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001427
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001418
Curated Selection
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