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EN2 (NM_001427) Human Recombinant Protein

Product Specifications

Background

Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. [provided by RefSeq, Jul 2008]

Synonyms

AUTS1, AUTS10; engrailed-2; engrailed homeobox 2; engrailed homolog 2

Gene ID

2020

UniProt

P19622

Accession Number mRNA

NM_001427

Chromosomal Location

7q36.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, ES Cell Differentiation/IPS

Molecular Weight

34 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

EN2

Species

Human

Protein ID

NP_001418

Overview

Recombinant protein of human engrailed homeobox 2 (EN2)

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2020

Uniprot URL

https://www.uniprot.org/uniprot/P19622

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001427

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001418

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