KCNE2 (NM_172201) Human Recombinant Protein
Product Specifications
Background
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a small integral membrane subunit that assembles with the KCNH2 gene product, a pore-forming protein, to alter its function. This gene is expressed in heart and muscle and the gene mutations are associated with cardiac arrhythmia. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human potassium voltage-gated channel, Isk-related family, member 2 (KCNE2)
Synonyms
ATFB4; LQT5; LQT6; MIRP1
Gene ID
9992
UniProt
Q9Y6J6
Accession Number mRNA
NM_172201
Chromosomal Location
21q22.11
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
14.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
KCNE2
Species
Human
Protein ID
NP_751951
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9992
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y6J6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_172201
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_751951
Frequently Asked Questions
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