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KCNE2 (NM_172201) Human Recombinant Protein

Product Specifications

Background

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a small integral membrane subunit that assembles with the KCNH2 gene product, a pore-forming protein, to alter its function. This gene is expressed in heart and muscle and the gene mutations are associated with cardiac arrhythmia. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human potassium voltage-gated channel, Isk-related family, member 2 (KCNE2)

Synonyms

ATFB4; LQT5; LQT6; MIRP1

Gene ID

9992

UniProt

Q9Y6J6

Accession Number mRNA

NM_172201

Chromosomal Location

21q22.11

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Transmembrane

Molecular Weight

14.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

KCNE2

Species

Human

Protein ID

NP_751951

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/9992

Uniprot URL

https://www.uniprot.org/uniprot/Q9Y6J6

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_172201

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_751951

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