PF4 (NM_002619) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum. [provided by RefSeq, Oct 2014]
Overview
Recombinant protein of human platelet factor 4 (PF4)
Synonyms
CXCL4; PF-4; SCYB4
Gene ID
5196
UniProt
P02776
Accession Number mRNA
NM_002619
Chromosomal Location
4q13.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Chemokine signaling pathway, Cytokine-cytokine receptor interaction
Field of Research
Chemokine signaling pathway, Cytokine-cytokine receptor interaction
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Activity
28120850
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Secreted Protein, Transmembrane
Molecular Weight
10.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PF4
Species
Human
Protein ID
NP_002610
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5196
Uniprot URL
https://www.uniprot.org/uniprot/P02776
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002619
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002610
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