What is the catalog number for RFC4 (NM_181573) Human Recombinant Protein?

The catalog number for RFC4 (NM_181573) Human Recombinant Protein is PH36870M5.

What sizes are available for RFC4 (NM_181573) Human Recombinant Protein?

RFC4 (NM_181573) Human Recombinant Protein is available in the following size(s): 20 µg.

Is RFC4 (NM_181573) Human Recombinant Protein in stock?

RFC4 (NM_181573) Human Recombinant Protein is currently made to order / not held in immediate stock. Contact us for lead time.

RFC4 (NM_181573) Human Recombinant Protein

Product Specifications

Background

The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC) . RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human replication factor C (activator 1) 4, 37kDa (RFC4), transcript variant 2

Synonyms

A1; RFC37

Gene ID

5984

UniProt

P35249

Accession Number mRNA

NM_181573

Chromosomal Location

3q27.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

DNA replication, Mismatch repair, Nucleotide excision repair

Field of Research

DNA replication, Mismatch repair, Nucleotide excision repair

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Stem cell - Pluripotency

Molecular Weight

39.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.