COG5 (NM_006348) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is one of eight proteins (Cog1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. The encoded protein is organized with conserved oligomeric Golgi complex components 6, 7 and 8 into a sub-complex referred to as lobe B. Alternative splicing results in multiple transcript variants. Mutations in this gene result in congenital disorder of glycosylation type 2I.[provided by RefSeq, Jan 2011]
Synonyms
CDG2I; GOLTC1; GTC90
Gene ID
10466
UniProt
Q9UP83
Accession Number mRNA
NM_006348
Chromosomal Location
7q22.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
94.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
COG5
Species
Human
Protein ID
NP_006339
Overview
Recombinant protein of human component of oligomeric golgi complex 5 (COG5), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10466
Uniprot URL
https://www.uniprot.org/uniprot/Q9UP83
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006348
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006339
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