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COG5 (NM_006348) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is one of eight proteins (Cog1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. The encoded protein is organized with conserved oligomeric Golgi complex components 6, 7 and 8 into a sub-complex referred to as lobe B. Alternative splicing results in multiple transcript variants. Mutations in this gene result in congenital disorder of glycosylation type 2I.[provided by RefSeq, Jan 2011]

Overview

Recombinant protein of human component of oligomeric golgi complex 5 (COG5), transcript variant 1

Synonyms

CDG2I; GOLTC1; GTC90

Gene ID

10466

UniProt

Q9UP83

Accession Number mRNA

NM_006348

Chromosomal Location

7q22.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

94.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

COG5

Species

Human

Protein ID

NP_006339

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/10466

Uniprot URL

https://www.uniprot.org/uniprot/Q9UP83

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_006348

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_006339

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