Collagen X (COL10A1) (NM_000493) Human Recombinant Protein
Product Specifications
Background
This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Unlike type VIII collagen, the other short chain collagen, type X collagen is a homotrimer. Mutations in this gene are associated with Schmid type metaphyseal chondrodysplasia (SMCD) and Japanese type spondylometaphyseal dysplasia (SMD) . [provided by RefSeq, Jul 2008]
Synonyms
Collagen, type X, alpha 1; collagen X, alpha-1 polypeptide; OTTHUMP00000017049; OTTHUMP00000040411; Schmid metaphyseal chondrodysplasia; type X collagen alpha 1
Gene ID
1300
UniProt
Q03692
Accession Number mRNA
NM_000493
Chromosomal Location
6q22.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
64.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
COL10A1
Species
Human
Protein ID
NP_000484
Overview
Recombinant protein of human collagen, type X, alpha 1 (COL10A1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1300
Uniprot URL
https://www.uniprot.org/uniprot/Q03692
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_000493
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_000484
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