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SLURP2 (NM_177458) Human Recombinant Protein

Product Specifications

Background

This gene encodes a novel, secreted member of the Ly6/uPAR (LU) superfamily of proteins containing the unique three-finger LU domain. This gene is mainly expressed in epithelial cells, including skin and keratinocytes, and is up-regulated in psoriatic skin lesions, suggesting its involvement in the pathophysiology of psoriasis. Alternatively spliced transcript variants have been found for this gene. Read-through transcription from the neighboring upstream gene (LYNX1) generates naturally-occurring transcripts (LYNX1-SLURP2) that encode a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Sep 2017]

Overview

Recombinant protein of human Ly6/neurotoxin 1 (LYNX1), transcript variant SLURP2

Synonyms

SLURP-2; SLURP2

Gene ID

432355

UniProt

P0DP57

Accession Number mRNA

NM_177458

Chromosomal Location

8q24.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

10 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

SLURP2

Species

Human

Protein ID

NP_803253

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/432355

Uniprot URL

https://www.uniprot.org/uniprot/P0DP57

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_177458

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_803253

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