ATP5F1D (NM_001687) Human Recombinant Protein
Product Specifications
Background
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c) . This gene encodes the delta subunit of the catalytic core. Alternatively spliced transcript variants encoding the same isoform have been identified. [provided by RefSeq, Jul 2008]
Synonyms
ATP5D; MC5DN5
Gene ID
513
UniProt
P30049
Accession Number mRNA
NM_001687
Chromosomal Location
19p13.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Alzheimer's disease, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease
Field of Research
Alzheimer's disease, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
15 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ATP5F1D
Species
Human
Protein ID
NP_001678
Overview
Recombinant protein of human ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit (ATP5D), nuclear gene encoding mitochondrial protein, transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/513
Uniprot URL
https://www.uniprot.org/uniprot/P30049
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001687
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001678
Curated Selection
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