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Inhibin beta C chain (INHBC) (NM_005538) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of homodimeric and heterodimeric activin complexes. The heterodimeric complex may function in the inhibition of activin A signaling. Transgenic mice overexpressing this gene exhibit defects in testis, liver and prostate. [provided by RefSeq, Aug 2016]

Overview

Recombinant protein of human inhibin, beta C (INHBC)

Synonyms

IHBC

Gene ID

3626

UniProt

P55103

Accession Number mRNA

NM_005538

Chromosomal Location

12q13.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Cytokine-cytokine receptor interaction, TGF-beta signaling pathway

Field of Research

Cytokine-cytokine receptor interaction, TGF-beta signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Secreted Protein

Molecular Weight

36.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

INHBC

Species

Human

Protein ID

NP_005529

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/3626

Uniprot URL

https://www.uniprot.org/uniprot/P55103

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_005538

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_005529

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