HABP4 (NM_014282) Human Recombinant Protein

Product Specifications

Background

RNA-binding protein that plays a role in the regulation of transcription, pre-mRNA splicing and mRNA translation (PubMed:14699138, PubMed:16455055, PubMed:19523114, PubMed:21771594) . Negatively regulates DNA-binding activity of the transcription factor MEF2C in myocardial cells in response to mechanical stress (By similarity) . Plays a role in pre-mRNA splicing regulation (PubMed:19523114) . Binds (via C-terminus) to poly (U) RNA (PubMed:19523114) . Involved in mRNA translation regulation, probably at the initiation step (PubMed:21771594) . Seems to play a role in PML-nuclear bodies formation (PubMed:28695742) .[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human hyaluronan binding protein 4 (HABP4)

Synonyms

IHABP-4; IHABP4; Ki-1/57; SERBP1L

Gene ID

22927

UniProt

Q5JVS0

Accession Number mRNA

NM_014282

Chromosomal Location

9q22.32

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

45.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.