HABP4 (NM_014282) Human Recombinant Protein
Product Specifications
Background
RNA-binding protein that plays a role in the regulation of transcription, pre-mRNA splicing and mRNA translation (PubMed:14699138, PubMed:16455055, PubMed:19523114, PubMed:21771594) . Negatively regulates DNA-binding activity of the transcription factor MEF2C in myocardial cells in response to mechanical stress (By similarity) . Plays a role in pre-mRNA splicing regulation (PubMed:19523114) . Binds (via C-terminus) to poly (U) RNA (PubMed:19523114) . Involved in mRNA translation regulation, probably at the initiation step (PubMed:21771594) . Seems to play a role in PML-nuclear bodies formation (PubMed:28695742) .[UniProtKB/Swiss-Prot Function]
Synonyms
IHABP-4; IHABP4; Ki-1/57; SERBP1L
Gene ID
22927
UniProt
Q5JVS0
Accession Number mRNA
NM_014282
Chromosomal Location
9q22.32
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
45.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HABP4
Species
Human
Protein ID
NP_055097
Overview
Recombinant protein of human hyaluronan binding protein 4 (HABP4)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/22927
Uniprot URL
https://www.uniprot.org/uniprot/Q5JVS0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_014282
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_055097
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