PIGR (NM_002644) Human Recombinant Protein
Product Specifications
Background
This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.[provided by RefSeq, Sep 2009]
Overview
Recombinant protein of human polymeric immunoglobulin receptor (PIGR)
Synonyms
FLJ22667; MGC125361; MGC125362
Gene ID
5284
UniProt
P01833
Accession Number mRNA
NM_002644
Chromosomal Location
1q32.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Secreted Protein, Transmembrane
Molecular Weight
81.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PIGR
Species
Human
Protein ID
NP_002635
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5284
Uniprot URL
https://www.uniprot.org/uniprot/P01833
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002644
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002635
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