Aurora A (AURKA) (NM_198433) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
AIK; ARK1; AURA; BTAK; PPP1R47; STK6; STK7; STK15
Gene ID
6790
UniProt
O14965
Accession Number mRNA
NM_198433
Chromosomal Location
20q13.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Oocyte meiosis
Field of Research
Oocyte meiosis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protein Kinase, Stem cell - Pluripotency
Molecular Weight
45.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
AURKA
Species
Human
Protein ID
NP_940835
Overview
Recombinant protein of human aurora kinase A (AURKA), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6790
Uniprot URL
https://www.uniprot.org/uniprot/O14965
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_198433
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_940835
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