Aurora A (AURKA) (NM_198433) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human aurora kinase A (AURKA), transcript variant 1

Synonyms

AIK; ARK1; AURA; BTAK; PPP1R47; STK6; STK7; STK15

Gene ID

6790

UniProt

O14965

Accession Number mRNA

NM_198433

Chromosomal Location

20q13.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Oocyte meiosis

Field of Research

Oocyte meiosis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Protein Kinase, Stem cell - Pluripotency

Molecular Weight

45.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.