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CTDSP1 (NM_021198) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the small C-terminal domain phosphatase (SCP) family of nuclear phosphatases. These proteins play a role in transcriptional regulation through specific dephosphorylation of phosphoserine 5 within tandem heptapeptide repeats of the C-terminal domain of RNA polymerase II. The encoded protein plays a role in neuronal gene silencing in non-neuronal cells, and may also inhibit osteoblast differentiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]

Overview

Recombinant protein of human CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 (CTDSP1), transcript variant 1

Synonyms

NIF3; NLI-IF; NLIIF; SCP1

Gene ID

58190

UniProt

Q9GZU7

Accession Number mRNA

NM_021198

Chromosomal Location

2q35

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Phosphatase

Molecular Weight

29 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

CTDSP1

Species

Human

Protein ID

NP_067021

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/58190

Uniprot URL

https://www.uniprot.org/uniprot/Q9GZU7

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_021198

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_067021

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