CTDSP1 (NM_021198) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the small C-terminal domain phosphatase (SCP) family of nuclear phosphatases. These proteins play a role in transcriptional regulation through specific dephosphorylation of phosphoserine 5 within tandem heptapeptide repeats of the C-terminal domain of RNA polymerase II. The encoded protein plays a role in neuronal gene silencing in non-neuronal cells, and may also inhibit osteoblast differentiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
Overview
Recombinant protein of human CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 (CTDSP1), transcript variant 1
Synonyms
NIF3; NLI-IF; NLIIF; SCP1
Gene ID
58190
UniProt
Q9GZU7
Accession Number mRNA
NM_021198
Chromosomal Location
2q35
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Phosphatase
Molecular Weight
29 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CTDSP1
Species
Human
Protein ID
NP_067021
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/58190
Uniprot URL
https://www.uniprot.org/uniprot/Q9GZU7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_021198
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_067021
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