TAS1R1 (NM_177540) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]

Overview

Recombinant protein of human taste receptor, type 1, member 1 (TAS1R1), transcript variant 3

Synonyms

GM148; GPR70; T1R1; TR1

Gene ID

80835

UniProt

Q7RTX1, A8K7J9

Accession Number mRNA

NM_177540

Chromosomal Location

1p36.31

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Taste transduction

Field of Research

Taste transduction

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Transmembrane

Molecular Weight

65 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.