TAS1R1 (NM_177540) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Synonyms
GM148; GPR70; T1R1; TR1
Gene ID
80835
UniProt
Q7RTX1, A8K7J9
Accession Number mRNA
NM_177540
Chromosomal Location
1p36.31
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Taste transduction
Field of Research
Taste transduction
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
65 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TAS1R1
Species
Human
Protein ID
NP_803884
Overview
Recombinant protein of human taste receptor, type 1, member 1 (TAS1R1), transcript variant 3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/80835
Uniprot URL
https://www.uniprot.org/uniprot/Q7RTX1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_177540
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_803884
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