IRF5 (NM_002200) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative promoter use and alternative splicing result in multiple transcript variants, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. [provided by RefSeq, Dec 2016]

Overview

Recombinant protein of human interferon regulatory factor 5 (IRF5), transcript variant 1

Synonyms

Interferon regulatory factor 5; SLEB10

Gene ID

3663

UniProt

Q13568

Accession Number mRNA

NM_002200

Chromosomal Location

7q32.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Toll-like receptor signaling pathway

Field of Research

Toll-like receptor signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Activity

26519527

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transcription Factors

Molecular Weight

56.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.