IRF5 (NM_002200) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative promoter use and alternative splicing result in multiple transcript variants, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. [provided by RefSeq, Dec 2016]
Synonyms
Interferon regulatory factor 5; SLEB10
Gene ID
3663
UniProt
Q13568
Accession Number mRNA
NM_002200
Chromosomal Location
7q32.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Toll-like receptor signaling pathway
Field of Research
Toll-like receptor signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Activity
26519527
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transcription Factors
Molecular Weight
56.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
IRF5
Species
Human
Protein ID
NP_002191
Overview
Recombinant protein of human interferon regulatory factor 5 (IRF5), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3663
Uniprot URL
https://www.uniprot.org/uniprot/Q13568
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002200
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002191
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