Amino terminal enhancer of split (AES) (NM_001130) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human amino-terminal enhancer of split (AES), transcript variant 2
Synonyms
AES; AES-1; AES-2; ESP1; GRG; Grg-5; GRG5
Gene ID
166
UniProt
Q08117, Q8WY48
Accession Number mRNA
NM_001130
Chromosomal Location
19p13.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transcription Factors
Molecular Weight
21.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TLE5
Species
Human
Protein ID
NP_001121
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/166
Uniprot URL
https://www.uniprot.org/uniprot/Q08117
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001130
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001121
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