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P16 ARC (ARPC5) (NM_005717) Human Recombinant Protein

Product Specifications

Background

This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p16 subunit, has yet to be determined. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

Overview

Recombinant protein of human actin related protein 2/3 complex, subunit 5, 16kDa (ARPC5)

Synonyms

ARC16; dJ127C7.3; p16-Arc

Gene ID

10092

UniProt

O15511

Accession Number mRNA

NM_005717

Chromosomal Location

1q25.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Fc gamma R-mediated phagocytosis, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton

Field of Research

Fc gamma R-mediated phagocytosis, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

16.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

ARPC5

Species

Human

Protein ID

NP_005708

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/10092

Uniprot URL

https://www.uniprot.org/uniprot/O15511

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_005717

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_005708

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