Histidine decarboxylase (HDC) (NM_002112) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes, including neurotransmission, gastric acid secretion, inflamation, and smooth muscle tone.[provided by RefSeq, Aug 2010]
Synonyms
MGC163399
Gene ID
3067
UniProt
P19113
Accession Number mRNA
NM_002112
Chromosomal Location
15q21.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Histidine metabolism, Metabolic pathways
Field of Research
Histidine metabolism, Metabolic pathways
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
74 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HDC
Species
Human
Protein ID
NP_002103
Overview
Recombinant protein of human histidine decarboxylase (HDC)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3067
Uniprot URL
https://www.uniprot.org/uniprot/P19113
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002112
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002103
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