Histidine decarboxylase (HDC) (NM_002112) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes, including neurotransmission, gastric acid secretion, inflamation, and smooth muscle tone.[provided by RefSeq, Aug 2010]

Overview

Recombinant protein of human histidine decarboxylase (HDC)

Synonyms

MGC163399

Gene ID

3067

UniProt

P19113

Accession Number mRNA

NM_002112

Chromosomal Location

15q21.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Histidine metabolism, Metabolic pathways

Field of Research

Histidine metabolism, Metabolic pathways

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

74 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.