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HENMT1 (NM_001102592) Human Recombinant Protein

Selected Variant

PH36513M5

Size: 20 µg

Product Specifications

Background

Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Homo sapiens chromosome 1 open reading frame 59 (C1orf59), transcript variant 2

Synonyms

C1orf59; HEN1

Gene ID

113802

UniProt

Q5T8I9

Accession Number mRNA

NM_001102592

Chromosomal Location

1p13.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

44.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

HENMT1

Species

Human

Protein ID

NP_001096062

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/113802

Uniprot URL

https://www.uniprot.org/uniprot/Q5T8I9

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001102592

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001096062

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