RASSF7 (NM_003475) Human Recombinant Protein
Product Specifications
Background
Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization.[UniProtKB/Swiss-Prot Function]
Synonyms
C11orf13; CFAP88; FAP88; HRAS1; HRC1
Gene ID
8045
UniProt
Q02833, A0A024RCE4
Accession Number mRNA
NM_003475
Chromosomal Location
11p15.5
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
39.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
RASSF7
Species
Human
Protein ID
NP_003466
Overview
Recombinant protein of human Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 (RASSF7), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8045
Uniprot URL
https://www.uniprot.org/uniprot/Q02833
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003475
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003466
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