Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

IKK gamma (IKBKG) (NM_001099856) Human Recombinant Protein

Product Specifications

Background

This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Mar 2016]

Synonyms

AMCBX1; EDAID1; FIP-3; FIP3; Fip3p; IKK-gamma; IKKAP1; IKKG; IMD33; IP; IP1; IP2; IPD2; NEMO; ZC2HC9

Gene ID

8517

UniProt

Q9Y6K9

Accession Number mRNA

NM_001099856

Chromosomal Location

Xq28

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Acute myeloid leukemia, Adipocytokine signaling pathway, Apoptosis, B cell receptor signaling pathway, Chemokine signaling pathway, Chronic myeloid leukemia, Cytosolic DNA-sensing pathway, Epithelial cell signaling in Helicobacter pylori infection, MAPK signaling pathway, NOD-like receptor signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prostate cancer, RIG-I-like receptor signaling pathway, Small cell lung cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway

Field of Research

Acute myeloid leukemia, Adipocytokine signaling pathway, Apoptosis, B cell receptor signaling pathway, Chemokine signaling pathway, Chronic myeloid leukemia, Cytosolic DNA-sensing pathway, Epithelial cell signaling in Helicobacter pylori infection, MAPK signaling pathway, NOD-like receptor signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prostate cancer, RIG-I-like receptor signaling pathway, Small cell lung cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Transcription Factors

Molecular Weight

48 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

IKBKG

Species

Human

Protein ID

NP_001093326

Overview

Recombinant protein of human inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (IKBKG), transcript variant 2

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/8517

Uniprot URL

https://www.uniprot.org/uniprot/Q9Y6K9

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001099856

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001093326

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Human NUMBL (NM_004756) AAV Particle
RC216869A1V 250 µL

Human NUMBL (NM_004756) AAV Particle

Ask
View Details
Rtn-3 Double Nickase Plasmid (m2)
sc-422764-NIC-2 20 µg

Rtn-3 Double Nickase Plasmid (m2)

Ask
View Details
Rat Monoclonal CD68/SR-D1 Antibody (FA-11) [mFluor Violet 610 SE]
NBP2-33337MFV610 0.1 mL

Rat Monoclonal CD68/SR-D1 Antibody (FA-11) [mFluor Violet 610 SE]

Ask
View Details
LentimiRa-Off-hsa-miR-3166 Vector
mh30488 500 ng

LentimiRa-Off-hsa-miR-3166 Vector

Ask
View Details