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ALDH8A1 (NM_022568) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the aldehyde dehydrogenase family of proteins. The encoded protein has been implicated in the synthesis of 9-cis-retinoic acid and in the breakdown of the amino acid tryptophan. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. In addition, this enzyme has been shown to catalyze the conversion of 2-aminomuconic semialdehyde to 2-aminomuconate in the kynurenine pathway of tryptophan catabolism. [provided by RefSeq, Jul 2018]

Overview

Recombinant protein of human aldehyde dehydrogenase 8 family, member A1 (ALDH8A1), transcript variant 1

Synonyms

ALDH12; DJ352A20.2

Gene ID

64577

UniProt

Q9H2A2

Accession Number mRNA

NM_022568

Chromosomal Location

6q23.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

53.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

ALDH8A1

Species

Human

Protein ID

NP_072090

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/64577

Uniprot URL

https://www.uniprot.org/uniprot/Q9H2A2

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_022568

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_072090

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