ALDH8A1 (NM_022568) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the aldehyde dehydrogenase family of proteins. The encoded protein has been implicated in the synthesis of 9-cis-retinoic acid and in the breakdown of the amino acid tryptophan. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. In addition, this enzyme has been shown to catalyze the conversion of 2-aminomuconic semialdehyde to 2-aminomuconate in the kynurenine pathway of tryptophan catabolism. [provided by RefSeq, Jul 2018]
Overview
Recombinant protein of human aldehyde dehydrogenase 8 family, member A1 (ALDH8A1), transcript variant 1
Synonyms
ALDH12; DJ352A20.2
Gene ID
64577
UniProt
Q9H2A2
Accession Number mRNA
NM_022568
Chromosomal Location
6q23.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
53.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ALDH8A1
Species
Human
Protein ID
NP_072090
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/64577
Uniprot URL
https://www.uniprot.org/uniprot/Q9H2A2
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_022568
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_072090
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