AKAP7 (NM_004842) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Apr 2011]
Overview
Recombinant protein of human A kinase (PRKA) anchor protein 7 (AKAP7), transcript variant alpha
Synonyms
AKAP15; AKAP18
Gene ID
9465
UniProt
O43687, Q2TAJ5, Q6P4D3
Accession Number mRNA
NM_004842
Chromosomal Location
6q23.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
8.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
AKAP7
Species
Human
Protein ID
NP_004833
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9465
Uniprot URL
https://www.uniprot.org/uniprot/O43687
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004842
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004833
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