Midkine (MDK) (NM_002391) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of a small family of secreted growth factors that binds heparin and responds to retinoic acid. The encoded protein promotes cell growth, migration, and angiogenesis, in particular during tumorigenesis. This gene has been targeted as a therapeutic for a variety of different disorders. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012]
Synonyms
ARAP; MK; NEGF2
Gene ID
4192
UniProt
P21741
Accession Number mRNA
NM_002391
Chromosomal Location
11p11.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Secreted Protein, Transmembrane
Molecular Weight
15.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MDK
Species
Human
Protein ID
NP_002382
Overview
Recombinant protein of human midkine (neurite growth-promoting factor 2) (MDK), transcript variant 3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4192
Uniprot URL
https://www.uniprot.org/uniprot/P21741
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002391
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002382
Curated Selection
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