Midkine (MDK) (NM_002391) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of a small family of secreted growth factors that binds heparin and responds to retinoic acid. The encoded protein promotes cell growth, migration, and angiogenesis, in particular during tumorigenesis. This gene has been targeted as a therapeutic for a variety of different disorders. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012]

Overview

Recombinant protein of human midkine (neurite growth-promoting factor 2) (MDK), transcript variant 3

Synonyms

ARAP; MK; NEGF2

Gene ID

4192

UniProt

P21741

Accession Number mRNA

NM_002391

Chromosomal Location

11p11.2

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Secreted Protein, Transmembrane

Molecular Weight

15.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.