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BRF1 (NM_001519) Human Recombinant Protein

Selected Variant

PH36434M5

Size: 20 µg

Product Specifications

Background

This gene encodes one of the three subunits of the RNA polymerase III transcription factor complex. This complex plays a central role in transcription initiation by RNA polymerase III on genes encoding tRNA, 5S rRNA, and other small structural RNAs. The gene product belongs to the TF2B family. Several alternatively spliced variants encoding different isoforms, that function at different promoters transcribed by RNA polymerase III, have been identified. [provided by RefSeq, Jun 2011]

Overview

Recombinant protein of human BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae) (BRF1), transcript variant 1

Synonyms

BRF; BRF-1; CFDS; GTF3B; hBRF; HEL-S-76p; TAF3B2; TAF3C; TAFIII90; TF3B90; TFIIIB90

Gene ID

2972

UniProt

Q92994

Accession Number mRNA

NM_001519

Chromosomal Location

14q32.33

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transcription Factors

Molecular Weight

73.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

BRF1

Species

Human

Protein ID

NP_001510

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2972

Uniprot URL

https://www.uniprot.org/uniprot/Q92994

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001519

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001510

Price

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