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HDAC7A (NM_016596) Human Recombinant Protein

Product Specifications

Background

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human histone deacetylase 7A (HDAC7A), transcript variant 2

Synonyms

HD7; HD7A; HDAC7A

Gene ID

51564

UniProt

Q8WUI4

Accession Number mRNA

NM_016596

Chromosomal Location

12q13.11

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Transcription Factors

Molecular Weight

99.5

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

HDAC7A

Species

Human

Protein ID

NP_057680

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/51564

Uniprot URL

https://www.uniprot.org/uniprot/Q8WUI4

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_016596

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_057680

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