HDAC7A (NM_016596) Human Recombinant Protein
Product Specifications
Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human histone deacetylase 7A (HDAC7A), transcript variant 2
Synonyms
HD7; HD7A; HDAC7A
Gene ID
51564
UniProt
Q8WUI4
Accession Number mRNA
NM_016596
Chromosomal Location
12q13.11
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transcription Factors
Molecular Weight
99.5
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HDAC7A
Species
Human
Protein ID
NP_057680
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/51564
Uniprot URL
https://www.uniprot.org/uniprot/Q8WUI4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_016596
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_057680
Frequently Asked Questions
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