CTNNA3 (NM_013266) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein that belongs to the vinculin/alpha-catenin family. The encoded protein plays a role in cell-cell adhesion in muscle cells. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia, familial 13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Overview
Recombinant protein of human catenin (cadherin-associated protein), alpha 3 (CTNNA3), transcript variant 1
Synonyms
ARVD13; VR22
Gene ID
29119
UniProt
Q9UI47, A8K141
Accession Number mRNA
NM_013266
Chromosomal Location
10q21.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Endometrial cancer, Leukocyte transendothelial migration, Pathways in cancer, Tight junction
Field of Research
Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Endometrial cancer, Leukocyte transendothelial migration, Pathways in cancer, Tight junction
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
99.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CTNNA3
Species
Human
Protein ID
NP_037398
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/29119
Uniprot URL
https://www.uniprot.org/uniprot/Q9UI47
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_013266
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_037398
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