Plunc (BPIFA1) (NM_016583) Human Recombinant Protein
Product Specifications
Background
This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The encoded antimicrobial protein displays antibacterial activity against Gram-negative bacteria. It is thought to be involved in inflammatory responses to irritants in the upper airways and may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only three are known. [provided by RefSeq, Aug 2014]
Synonyms
BA49G10.5; LUNX; NASG; PLUNC; SPLUNC1; SPURT
Gene ID
51297
UniProt
Q9NP55
Accession Number mRNA
NM_016583
Chromosomal Location
20q11.21
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Secreted Protein
Molecular Weight
24.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
BPIFA1
Species
Human
Protein ID
NP_057667
Overview
Recombinant protein of human palate, lung and nasal epithelium associated (PLUNC), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/51297
Uniprot URL
https://www.uniprot.org/uniprot/Q9NP55
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_016583
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_057667
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items