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Plunc (BPIFA1) (NM_016583) Human Recombinant Protein

Product Specifications

Background

This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The encoded antimicrobial protein displays antibacterial activity against Gram-negative bacteria. It is thought to be involved in inflammatory responses to irritants in the upper airways and may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only three are known. [provided by RefSeq, Aug 2014]

Synonyms

BA49G10.5; LUNX; NASG; PLUNC; SPLUNC1; SPURT

Gene ID

51297

UniProt

Q9NP55

Accession Number mRNA

NM_016583

Chromosomal Location

20q11.21

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Secreted Protein

Molecular Weight

24.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

BPIFA1

Species

Human

Protein ID

NP_057667

Overview

Recombinant protein of human palate, lung and nasal epithelium associated (PLUNC), transcript variant 1

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/51297

Uniprot URL

https://www.uniprot.org/uniprot/Q9NP55

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_016583

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_057667

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