VCAM1 (NM_080682) Human Recombinant Protein

Product Specifications

Background

This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010]

Overview

Recombinant protein of human vascular cell adhesion molecule 1 (VCAM1), transcript variant 2

Synonyms

CD106; INCAM-100

Gene ID

7412

UniProt

P19320

Accession Number mRNA

NM_080682

Chromosomal Location

1p21.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Cell adhesion molecules (CAMs), Leukocyte transendothelial migration

Field of Research

Cell adhesion molecules (CAMs), Leukocyte transendothelial migration

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, ES Cell Differentiation/IPS, Transmembrane

Molecular Weight

68.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.