HMGN3 (NM_004242) Human Recombinant Protein
Selected Variant
PH36370M5
Size: 20 µg
Product Specifications
Background
The protein encoded by this gene binds thyroid hormone receptor beta in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. There is a related pseudogene on chromosome 1. [provided by RefSeq, Jan 2016]
Overview
Recombinant protein of human high mobility group nucleosomal binding domain 3 (HMGN3), transcript variant 1
Synonyms
PNAS-24; PNAS-25; TRIP7
Gene ID
9324
UniProt
Q15651
Accession Number mRNA
NM_004242
Chromosomal Location
6q14.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
10.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HMGN3
Species
Human
Protein ID
NP_004233
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9324
Uniprot URL
https://www.uniprot.org/uniprot/Q15651
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004242
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004233
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