Gemin 8 (GEMIN8) (NM_017856) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010]
Overview
Recombinant protein of human gem (nuclear organelle) associated protein 8 (GEMIN8), transcript variant 3
Synonyms
FAM51A1
Gene ID
54960
UniProt
Q9NWZ8, A0A024RBX2
Accession Number mRNA
NM_017856
Chromosomal Location
Xp22.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
28.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GEMIN8
Species
Human
Protein ID
NP_060326
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/54960
Uniprot URL
https://www.uniprot.org/uniprot/Q9NWZ8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_017856
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_060326
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