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MVP (NM_017458) Human Recombinant Protein

Product Specifications

Background

This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]

Overview

Recombinant protein of human major vault protein (MVP), transcript variant 1

Synonyms

LRP; VAULT1

Gene ID

9961

UniProt

Q14764, X5D2M8

Accession Number mRNA

NM_017458

Chromosomal Location

16p11.2

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

99.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

MVP

Species

Human

Protein ID

NP_059447

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/9961

Uniprot URL

https://www.uniprot.org/uniprot/Q14764

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_017458

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_059447

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