MVP (NM_017458) Human Recombinant Protein
Product Specifications
Background
This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]
Overview
Recombinant protein of human major vault protein (MVP), transcript variant 1
Synonyms
LRP; VAULT1
Gene ID
9961
UniProt
Q14764, X5D2M8
Accession Number mRNA
NM_017458
Chromosomal Location
16p11.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
99.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MVP
Species
Human
Protein ID
NP_059447
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9961
Uniprot URL
https://www.uniprot.org/uniprot/Q14764
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_017458
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_059447
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