ARMETL1 (CDNF) (NM_001029954) Human Recombinant Protein

Product Specifications

Background

Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA) -induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human arginine-rich, mutated in early stage tumors-like 1 (ARMETL1)

Synonyms

ARMETL1

Gene ID

441549

UniProt

Q49AH0

Accession Number mRNA

NM_001029954

Chromosomal Location

10p13

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

20.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.