ARMETL1 (CDNF) (NM_001029954) Human Recombinant Protein
Product Specifications
Background
Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA) -induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human arginine-rich, mutated in early stage tumors-like 1 (ARMETL1)
Synonyms
ARMETL1
Gene ID
441549
UniProt
Q49AH0
Accession Number mRNA
NM_001029954
Chromosomal Location
10p13
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
20.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CDNF
Species
Human
Protein ID
NP_001025125
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/441549
Uniprot URL
https://www.uniprot.org/uniprot/Q49AH0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001029954
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001025125
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