PLA2R (PLA2R1) (NM_001007267) Human Recombinant Protein

Product Specifications

Background

This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Sep 2010]

Overview

Purified recombinant protein of Homo sapiens phospholipase A2 receptor 1, 180kDa (PLA2R1), transcript variant 2

Synonyms

CLEC13C; PLA2-R; PLA2G1R; PLA2IR; PLA2R

Gene ID

22925

UniProt

Q13018

Accession Number mRNA

NM_001007267

Chromosomal Location

2q24.2

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Transmembrane

Molecular Weight

150.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.