PLA2R (PLA2R1) (NM_001007267) Human Recombinant Protein
Product Specifications
Background
This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Sep 2010]
Synonyms
CLEC13C; PLA2-R; PLA2G1R; PLA2IR; PLA2R
Gene ID
22925
UniProt
Q13018
Accession Number mRNA
NM_001007267
Chromosomal Location
2q24.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
150.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PLA2R1
Species
Human
Protein ID
NP_001007268
Overview
Purified recombinant protein of Homo sapiens phospholipase A2 receptor 1, 180kDa (PLA2R1), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/22925
Uniprot URL
https://www.uniprot.org/uniprot/Q13018
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001007267
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001007268
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