UBE2D3 (NM_181886) Human Recombinant Protein
Product Specifications
Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. [provided by RefSeq, Jan 2017]
Synonyms
E2 (17) KB3; UBC4/5; UBCH5C
Gene ID
7323
UniProt
P61077, A0A024RDH2
Accession Number mRNA
NM_181886
Chromosomal Location
4q24
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Ubiquitin mediated proteolysis
Field of Research
Ubiquitin mediated proteolysis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
16.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
UBE2D3
Species
Human
Protein ID
NP_871615
Overview
Purified recombinant protein of Homo sapiens ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) (UBE2D3), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7323
Uniprot URL
https://www.uniprot.org/uniprot/P61077
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_181886
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_871615
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